
The anus is the opening at the end of the large intestine, below the rectum, where bowel movements leave the body. The beginning of the anal cancer is seen when the healthy cells grow in an uncontrolled manner, thereby, forming masses of cells called as tumours. The infected cells can be squamous cell, cloacogenic cell, anal lining cell and basal cell. A majority of the reported anal cancers are the squamous cell carcinomas. When the cells are at the beginning sate, they appears to be normal. This is the dysplasia state of the cancer. Dysplasia in the anus is called anal intraepithelial neoplasia (AIN) or anal squamous intraepithelial lesions (SILs). Increasing prevalence of the anal cancer and sexually transmitted diseases along with the growing geriatric population are the major drivers for the market growth during the forecast period. In 2017, according to the American Cancer Society, 8,200 new cases of the anal cancer were reported in the U.S. causing 1,100 deaths. Moreover, it is reported that the anal cancer is rare in people younger than 35 years in age and is found mainly in the geriatric population. According to the World Health Organization, the number of people aging 65 or older is projected to grow from an estimated 524 million in 2010 to nearly 1.5 billion in 2050, with most of the increase in developing countries. However, factors like lack of awareness and low per capita healthcare expenditure are estimated to restrain the market growth during the forecast period.