Bio-identical Hormone Therapy Review

Developed by Dr. Gino Tutera, M.D., F.A.C.O.G., more than two decades ago, SottoPelle® is an evidence-based proprietary method of BHRT. It differs from traditional Hormone Replacement Therapy (HRT) by offering a precise, Web-based, individualized dosage delivery system (BioCalc®) prescribed for each patient’s specific medical needs. It is administered subcutaneously through natural pellets whose molecular structure mimics the body’s natural hormones. The treatment uses the highest quality plant-based pellets and SottoPelle®’s patent-pending BioCalc® dosing application via a unique insertion technique to generate steady and consistent serum levels for patients. Unlike many of today’s synthetic hormones with one-size-fits-all generic doses, SottoPelle® delivers a consistent flow of natural hormones on a 24-7 basis to support better health. For more information about SottoPelle® and BioCalc®, visit