For many years now, the preferred Toenail Fungus Treatment of doctors has been Lamisil or Sporanox treatments. These medications do come with serious side effects. The FDA now advises health care professionals to avoid the use of Sporanox in patients with congestive heart failure or a history of this condition. Both Lamisil and Sporanox have been linked to serious liver problems, even death. Patients concerned about using either of these medications now have a new option when it comes to treating this common infection. Laser treatment has been shown to be very effective at killing the fungus responsible for nail infections.