Atopic Dermatitis(AD) as the chronic or recurrent inflammatory skin disease, which belongs to the group of allergic disorders that includes food allergy, allergic rhinitis, and asthma. It is a chronic inflammatory skin disease and the clinical picture is characterized by widespread skin lesions, which manifest as red, itchy, swollen, cracked, weeping lesions with crusting/scaling, intractable pruritus and enhanced susceptibility to bacterial and viral skininfections. Atopic Dermatitis is classified as: Mild, Moderate and . In patients with moderate-to-severe Atopic Dermatitis, Pruritus is the most common and persistent disease that is prevalent. It is classified as Controlled Atopic Dermatitis and Uncontrolled Atopic Dermatitis on the basis of the disease controlled by using therapies. Uncontrolled Atopic Dermatitis is defined as currently flaring Atopic Dermatitis, deteriorating/changeable Atopic Dermatitis that cannot be controlled by therapies.