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Interstitial Cystitis(IC), also called as Painful Bladder Syndrome, is a chronic condition causing bladder pressure, bladder pain and sometimes pelvic pain. The pain ranges from mild discomfort to severe levels. Bladder is a hollow, muscular organ that stores urine. The bladder expands until it is full and then give signals to the brain that it is time to urinate, communicating through the pelvic nerves. IC can be of two types: Non-Ulcerative and Ulcerative. Non-Ulcerative is found in 90% of the population suffering from Interstitial Cystitis. It is characterized by pinpoint hemorrhages called as glomerulations. Ulcerative IC is mainly characterized by Hunner's ulcers and the patches that bleed on bladder walls. However, IC was considered as a rare disease; this came from a situation of underdiagnosis and misunderstandings about the nature of the IC. It was not until late 1970s, when researchers proved that the vast majority of patients with IC has no Hunner lesions.

Uveal melanoma is the most common intraocular malignancy and arises from melanocytes in the iris (anterior), ciliary body, or choroid (posterior). Iris melanomas have the best prognosis, whereas melanomas of the ciliary body have the least favourable prognosis. Most uveal tract melanomas originate in the choroid while the iris is the least common. The typical choroidal melanoma is a brown, elevated, dome-shaped sub retinal mass. The degree of pigmentation ranges from dark brown to totally amelanotic. Melanomas of the choroid generally are more malignant. Males have a higher incidence than females. UM is diagnosed mostly at older ages, with a progressively rising, age-specific, incidence rate that peaks near the age of 70 years. Most Uveal melanomas are initially completely asymptomatic. As the tumour enlarges, it may cause distortion of the pupil (iris melanoma), blurred vision (Ciliary body melanoma), or markedly decreased visual acuity caused by secondary retinal detachment (choroidal melanoma). Serous detachment of the retina may occur.

Acromegaly is a rare but serious hormonal disorder caused by the excessive growth hormone (GH) in the body. The excessive GH usually comes from benign, or noncancerous, tumours in the pituitary, known as pituitary adenoma. This condition is the most often diagnosed in middle-aged adults, though the symptoms can appear at any age. In most of the cases, it is treatable, but because of its slow and sneaky onset, the disease remains undiagnosed. If left untreated, the disease can result in serious illness and premature death. The serious health complications are Type 2 diabetes, high blood pressure, increased risk of cardiovascular disease, and arthritis. The condition affects males and females in equal numbers.

Acute Respiratory Distress Syndrome (ARDS) is a life- threatening severe orphan disease in which the air sacs present in alveoli are filled with fluid and lower the amount of oxygen in blood. Thus, enough oxygen is not supplied to the body. Inflammation may occur throughout the lungs. The condition is also classified on the basis of severity of disease as Mild ARDS, Moderate ARDS and Severe ARDS. It is generally characterized into three stages such as exudative stage, fibro proliferative (or proliferative) stage, resolution and recovery stage.

According to the report of DelveInsight "Cushing's Syndrome (CS) - Market Insights, Epidemiology and Market Forecast – 2027" United States accounts for the highest number of cases of Cushing's syndrome. A total of 20,110 prevalent cases were diagnosed in 2015. The total number of Cushing's syndrome cases is expected to reach 20,841 in 2023. Due to decline in the population in 2011, there is a marginal decline in the total Cushing's syndrome patients. Cushing's syndrome in Germany accounts total of 5,346 prevalent cases in 2015.

Aneurysmal Subarachnoid Hemorrhage (SAH) is defined as a condition where a brain aneurysm ruptures and causes bleeding into the compartment surrounding the brain, the subarachnoid space as per definition given by Brain Aneurysm Foundation. Often the aneurysm heals over, bleeding stops, and the person survives. In more serious cases, the bleeding may cause brain damage with paralysis or coma. In the most severe cases, the bleeding leads to death. Aneurysmal subarachnoid hemorrhage (SAH) is more common in women than in men as estimated by De Marchis GM et.al. 2017. Subarachnoid hemorrhage (SAH) is a common and frequently devastating condition, accounting for around 5% of all strokes.

Allergic Rhinitis is a common chronic respiratory disorder, which occurs due to the exposure to indoor and outdoor allergens such as dust mites, insects, animal dander, molds, and pollens. It is characterized by signs and symptoms such as Rhinorrhea, Nasal Congestion, Obstruction, and Pruritus and is associated with comorbidities such as Asthma. As per American Academy of Allergy Asthma and Immunology, approximately 10% and 30% of the worldwide population are suffering from Allergic Rhinitis. As per Allergic Rhinitis Impact on Asthma (ARIA) organization, Allergic Rhinitis is classified as following:

DelveInsight's "Actinic Keratosis - Market Insights, Epidemiology and Market Forecast 2027" report provides the detailed overview of the disease and in depth understanding of historical and forecasted epidemiology. It highlights the existing treatment patterns, potential upcoming drugs and also identifies best of the market opportunities by providing the current and forecasted market revenue, sales trends, and drug uptake during the study period from 2016-2027.

Neuroblastoma originates in adrenal medulla and paraspinal or periaortic regions, where sympathetic nervous system tissue is present. It is the third most common childhood cancer, after leukemia and brain tumors, and is the most common solid extracranial tumor in children. Neuroblastoma is staged by the two systems that are INSS and INRGSS. Neuroblastoma cancer occurs most often in infants and young children, and is rarely found in children older than 10 years.

Hepatitis Delta is the most severe form of viral hepatitis in humans and is caused by infection with the hepatitis delta virus (HDV). The defective RNA virus requires the help of hepatitis B virus (HBV) for virion assembly and penetration into hepatocytes. The help obtained by the HDV genome from HBV is limited to the sharing of envelope proteins. These proteins are needed to facilitate the assembly of the HDV genome into new virus particles, an, in turn, to allow the attachment and entry of HDV into new host cells. Hepatitis D has segmented on the basis if severity as Fulminant Hepatitis, Acute HDV & chronic HDV.