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Diabetic Macular Edema - Pipeline Review, H2 2017, provides an overview of the Diabetic Macular Edema (Metabolic Disorders) pipeline landscape.

The nomenclature for such devices includes transcatheter heart valve replacement (THVR) and percutaneous heart valve replacement. In this instance, 'percutaneous' is used interchangeably with 'transcatheter'. For the sake of this report, these devices will be referred to as transcatheter heart valve replacement devices. The industry standard is to define these products further by denoting the specific heart valve for which the device is indicated. Examples of this would be transcatheter aortic valve replacement (TAVR), transcatheter mitral valve replacement (TMVR) devices and transcatheter pulmonary valve replacement (TPVR) devices.

Transcatheter heart valve repair is often referred to as percutaneous heart valve repair (PHVR). The naming conventions are also changed to account for the specific heart valve that the device is indicated for. Devices currently approved and undergoing trials are intended for use on the mitral valve and are thus labeled as transcatheter mitral valve replacement (TMVR) devices.

Coronary Artery Disease (CAD) (Ischemic Heart Disease) - Pipeline Review, H2 2017, provides an overview of the Coronary Artery Disease (CAD) (Ischemic Heart Disease) (Cardiovascular) pipeline landscape.

Angina is the medical term used for describing the chest pain or discomfort that an individual can experience when the heart does not receive an adequate supply of oxygen-rich blood. This can occur when the arteries supplying blood flow to the heart muscle become partially blocked or narrowed by the accumulation of fatty deposits known as plaque. This condition, where plaque progressively builds up in the interior walls of the arteries, resulting in reduced blood flow to the myocardium, ischemia and angina, is known as coronary atherosclerosis.

Botulism - Pipeline Review, H2 2017, provides an overview of the Botulism (Infectious Disease) pipeline landscape.

The vast majority of commercially available tissue valves are xenograft valves derived from animals. Usually, the valves are porcine, meaning from a pig, or bovine, meaning from a cow. The porcine heart is most similar to the human heart and therefore represents the best anatomical fit for replacement. The tissue of the pericardial sac is particularly well suited for a valve leaflet due to its extremely durable physical properties. Before implantation, the tissue undergoes multiple chemical treatments to make it suitable for replacement in the human heart. The tissue is sterilized so that the biological markers are removed, thereby eliminating a response from the host's immune system.

Mumps - Pipeline Review, H2 2017, provides an overview of the Mumps (Infectious Disease) pipeline landscape.

Cardiac surgery involves the heart and the great vessels connected to the heart. It is often performed to treat ischemic heart disease, congenital heart disease, valvular heart disease as well as heart transplantation. The first cardiac surgeries were performed in the 19th century on the pericardium, the sac that surrounds the heart. The first surgery on the heart itself was performed in 1895 in Oslo, Norway. Surgeon Axel Cappelen ligated the bleeding coronary artery of a 24-year-old patient who had been stabbed under his left arm.

Bacterial Vaginosis - Pipeline Review, H2 2017, provides an overview of the Bacterial Vaginosis (Infectious Disease) pipeline landscape.