
Parkinson's disease is a central nervous system disorder affecting motor neuron activities, characterized by tremor, rigidity, dementia, depression etc. According to GDB 2013 Mortality and Causes of Death Collaborators report, in 2013, 53 Mn people were living with Parkinson's disease while the disease caused 103,000 deaths globally. Risk of Parkinson's disease increases with age and the disease mainly affects person over 50 years of age. Treatment for the Parkinson's disease in mainly symptomatic and no curative treatment options are available. The main aim of the Parkinson's disease treatment is to provide control on signs and symptoms such as shakiness in hands, difficulty with walking, slowness of movement etc. Therapeutic approach for each person varies according to his or her symptoms. Treatment options include medication or surgical treatment. Levodopa in combination with carbidopa is considered as a gold standard for symptomatic treatment of Parkinson's disease. Surgical treatment options include deep brain stimulation and Carbidopa/levodopa enteral suspension therapy. However, surgical therapy is effective only for patients who have previously responded to Levodopa therapy. Some of the commercially available drugs for treatment of Parkinson's disease are Cycloset, Parlodel (Bromocriptine Mesylate), Requip (ropinirole), Rytary, Azilect, Northera, Stalevo, Comtess/Comtan and others. Over the past decade, great progress has been made in the treatment of Parkinson's disease such as identification of new therapeutic targets through genetic research, understanding the common mutations that contribute to Parkinson's disease etc.