Small animal imaging technology has marked itself as the most useful tool in preclinical research globally. The technology has proved to be of great importance in developmental biology studies and drug development research programs. Being non-invasive, longitudinal studies are possible with accurate and detailed analysis. The global small animal imaging market has been studied from three main perspectives: by devices, by reagents, and by application areas. The devices in the preclinical imaging market include micro-computed tomography (CT), micro-magnetic resonance imaging (MRI), micro-positron emission tomography (PET) and micro-single positron emission computed tomography (SPECT), multimodal imaging, optical imaging, micro-ultrasound imaging and micro-photoacoustic tomography (PAT). The contrast reagents market has been studied for CT, MRI, nuclear imaging, optical imaging and ultrasound imaging technologies. Although small animal imaging has been extensively used in various research areas, the market for key application segments has been estimated. These segments include oncology, cardiology, autoimmune, neurology and psychiatry, and other applications. A detailed market analysis and forecast for each of these segments have been provided in this study in terms of market revenue (USD million) for the period 2012 to 2020.