
Ketoprofen is an analgesic, under the class of medication known as non-steroidal anti-inflammatory drug (NSAID). Ketoprofen is used for the treatment of pain, fever and inflammation. Ketoprofen acts on cyclooxygenase enzyme, to reduce the levels of prostaglandin chemicals, which causes fever, pain and inflammation. Ketoprofen is effective in treating conditions such as osteoarthritis, ankylosing spondylosis, gout, lower back pain, sprain, pain after surgery and rheumatoid arthritis. However, ketoprofen has various side effects such as loss of appetite, nausea, headaches, stomach pain, liver problems, vomiting and indigestion. In addition, ketoprofen may also cause fatal blood vessels and heart problems. Some of the medicines, such as aspirin, lithium, ACE inhibitors, ciclosporin, pentoxifylline, warfarin and methotrexate, interact with ketoprofen leading to various complications. Ketoprofen interacts with these medicines and causes complications such as blood pressure lowering and lithium toxicity.