Cardiac disease is a group of disorders of blood vessels and heart. Congenital heart defects, coronary artery disease and heart rhythm problems are some of the major cardiac diseases. Most common cause of heart disease is narrowing or blockage of blood vessels and coronary artery i.e. ischemic heart disease. Cardiac disease is mainly caused due to high cholesterol, smoking and high blood pressure. In addition, several other diseases such as, diabetes and obesity, and lifestyle changes such as poor nutrition, excessive alcohol and physical inactivity causes higher risk of cardiac diseases. In the U.S. heart disease is the leading cause of death in men and women. According to Centers for Disease Control and Prevention in 2010, in the U.S. approximately 600,000 people die due to heart disease. Prevention or control of heart disease is essential. Prevention from heart disease can be done by, controlling high blood pressure, lifestyle changes, lowering cholesterol, exercising and maintaining health weight. Heart disease treatment varies by condition. Cardiovascular implants have unique blood biocompatibility property, to ensure that the device is not rejected due to adverse thrombogenic or hemodynamic blood responses. There are various implantable cardiac devices such as cardiovascular stent, left ventricular assisted device, pacemakers, artificial hearts, defibrillators and vascular grafts. Pacemakers help in controlling the abnormal heart rhythm. Similarly, implantable defibrillator prevents cardiac arrest. Cardiac implant is composed of polymeric material such as hydrolytically degradable polyesters.