Fibrin glue is also called as fibrin sealant. It is a formulation used to create a fibrin clot. It is made up of fibrinogen and thrombin that are applied to the tissue sites to glue them together. Also, Fibrin glue is the type of surgical sealant used in surgeries for closure of wounds in surgical treatment. High internal bond strength, high surface adherence strength and others are the characteristics of fibrin glue. Fibrin glue is primarily used in cardiac surgery, pulmonary surgery, vascular surgeries, burn bleeding, orthopedic surgeries, plastic surgery, general surgery and lacerations of liver and spleen.