The Nobel Prize is a much-coveted award and some of the most recent recipients are those who unlocked the secret of pain sensation. David Julius PhD, University of California San Francisco, and Ardem Patapoutian PhD, Scripps Research in La Jolla have been awarded the Nobel Prize in Physiology or Medicine for groundbreaking research. Their focus is on the way that the body senses touch, as well as other stimuli, such as temperature. In particular, the scientists identified two ion channels that are necessary for the human body to respond to these stimuli. As a result of the research, it has been discovered that these mechanical pressure sensors control a broad spectrum of biological needs, from how our organs move to how we sense our body in time and space. The work is just the beginning of looking at how neurons gather information from organs and how this information makes its way to the brain.