
Conventional technology used in microbial cell cultivation have trailed behind array-based automated tools for genetic manipulation and discovery of biological systems. Due to this there is a need for systems that enable optimization, rapid testing, and bioprocess developments in low volume, parallel investigations with setup and in short duration that remain nearly independent of the number of bioreactors. Micro bioreactors is a step toward high-throughput bioprocess development, wherein fabrication, designing, fabrication and characterization of polymer based micro bioreactors are integrated with automated sensors and actuators. Plugin-and-flow microfluidic connectors along with fabricated polymer micro-optical lenses are combined in the micro bioreactors for fast set up and ease in use. Also there are various applications of micro bioreactors in possibility of culturing microbial cells for batch, continuous and fed-batch operations. Over the coming years the global micro bioreactors market is expected to witness substantial revenue growth owing to increasing applications and adoption of this technique for production of various by products.